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Zataria Multiflora Shown To Have Significant Inhibitory Effect on HSV-1


Zataria multiflora Boiss (Avishan-e-Shirazi in Persian and Sa’atar or Zaatar in ancient Iranian medical books) is a thyme-like plant and a member of Lamiaceae family that wildly grows in central and southern parts of Iran (Amin, 1991).1 It is used in traditional folk remedies for its antiseptic, analgesic (pain-relieving) and carminative (anti-flatulence and intestine soothing) properties (Amin, 19911; Mozaffarian, 19962). In addition to antibacterial activity (Eftekhar et al., 20113), essential oil of Zataria multiflora Boiss has been shown to have significant inhibitory effect on HSV-1 replication with IC50 values and selectivity indices of 0.0059% and 11.7, respectively (Mardani et al., 20124).

Antiviral activity of some plant oils against herpes simplex virus type 1 inVero cell culture

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1. Amin GR. Popular medicinal plants of Iran. Tehran: Iranian Research Institute of Medicinal Plants; 1991. 40 pp.
2. Muliawan SY, Kit LS, Devi S, Hashim O, Yusof R. Inhibitory potential of Quercuslusitanica extract on dengue virus type 2 replication. Southeast Asian J Trop Med Public Health.
3. Eftekhar F, Zamani S, Yusefzadi M, Hadian J, NejadEbrahimi S. Antibacterial activity of Zataria multiflora Boiss essential oil against extended spectrum β lactamase produced by urinary isolates of Klebsiella pneumonia. Jundishapur J Microbiol. 2011;4:S43–S49.

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